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Salicylic Acid or 2-Hydroxybenzoic Acid or 2-Hydroxybenzenecarboxylic acid BP Ph Eur USP Reagent Grade Manufacturers

Anmol Chemicals Group, established in 1976, is the pioneer manufacturer of Specialty chemicals, Pharmaceutical Excipients, Fragrance & Flavor chemicals in India. Anmol Chemicals Group has manufacturing facilities spread across Western India, representatives in Houston Chicago USA, Dubai and UAE. We also have toll manufacturing units for processing chemicals in a few countries around the world. We make IP, BP, USP, Ph. Eur., FCC or Food Grade, Analytical Reagent Grade, LR or Laboratory Reagent Grade, Pure and Technical Grades of various chemicals. All our items are analyzed to meet the required standards. We can supply the material in grams for your laboratory trial and in tons for your plant scale jobs.

Our manufacturing facility is FDA approved and cGMP, GLP (FDA) Approved, ISO 9001, ISO 14001, ISO 17025, ISO 45001, ISO 22000, HACCP, FSSAI, FSSC 22000, Halal and Kosher certified. We are registered with "REACH" for export to European countries. Solid materials can be customized for particle size, shape and bulk density. We observe WHO Good Manufacturing Practice and Good Laboratory Practice. We are a STAR Export House and “Authorised Economic Operator” as per Indian customs.

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Salicylic Acid or 2-Hydroxybenzoic Acid or 2-Hydroxybenzenecarboxylic acid SDS of Manufacturers

Salicylic Acid Manufacturers

Synonyms: Salicylic Acid or 2-Hydroxybenzoic Acid or 2-Hydroxybenzenecarboxylic acid
CAS Number: 69-72-7, Molecular Weight: 138.12, Chemical Formula: C7H6O3, EINECS EC Number: 200-712-3, FEMA: ----,

Salicylic acid is used in the production of other pharmaceuticals. Salicylic acid as a medication is used most commonly to help remove the outer layer of the skin. As such, it is used to treat warts, psoriasis, acne vulgaris, ringworm, dandruff, and ichthyosis. Salicylic acid is also used as a food preservative, bactericide, and an antiseptic.

Salicylic Acid BP Ph Eur Specifications:
C7H6O3 --- 138.1 --- CAS 69-72-7
Action and use: Keratolytic.

DEFINITION
2-Hydroxybenzenecarboxylic acid.
Content: 99.0 per cent to 100.5 per cent (dried substance).

CHARACTERS
Appearance: White or almost white, crystalline powder or white or colourless, acicular crystals.
Solubility: Slightly soluble in water, freely soluble in ethanol (96 per cent), sparingly soluble in methylene chloride.

IDENTIFICATION
First identification: A, B
Second identification: A, C
A. Melting point: 158C to 161C.
B. Infrared absorption spectrophotometry
C. Dissolve about 30 mg in 5 mL of 0.05 M sodium hydroxide, neutralise if necessary and dilute to 20 mL with water. 1 mL of the solution gives reaction (a) of salicylates.

TESTS
Solution S: Dissolve 2.5 g in 50 mL of boiling distilled water, cool and filter.
Appearance of solution: The solution is clear and colourless.
Dissolve 1 g in 10 mL of ethanol (96 per cent).Related substances: To pass the test.
Chlorides: Maximum 100 ppm.
Sulfates: Maximum 200 ppm.
Loss on drying: Maximum 0.5 per cent, determined on 1.000 g by drying in a desiccator.
Sulfated ash: Maximum 0.1 per cent, determined on 2.0 g.

ASSAY
Dissolve 0.120 g in 30 mL of ethanol (96 per cent) and add 20 mL of water. Titrate with 0.1 M sodium hydroxide, using 0.1 mL of phenol red solution as indicator.
1 mL of 0.1 M sodium hydroxide is equivalent to 13.81 mg of C7H6O3.

STORAGE
Protected from light.


Salicylic Acid USP Grade Specifications:
C7H6O3 --- 138.12
Benzoic acid, 2-hydroxy-
Salicylic acid CAS 69-72-7

DEFINITION
Salicylic Acid contains NLT 98.0% and NMT 102.0% of salicylic acid (C7H6O3 ), calculated on the dried basis.

IDENTIFICATION
A.
Infrared Absorption
B. The retention time of the major peak of the Sample solution corresponds to that of the Standard solution, as obtained in the Assay.

ASSAY
To pass the test.

Acceptance criteria: 98.0%–102.0% on the dried basis.
Residue on Ignition: NMT 0.05%
Chloride and Sulfate:
Chloride: To pass the test (0.014%).
Sulfate: To pass the test (0.02%).
Organic Impurities: To pass the test.
Loss on Drying:
Analysis: Dry over silica gel for 3 h.
Acceptance criteria: NMT 0.5%
Packaging and Storage: Preserve in well-closed containers.


Salicylic Acid Analytical Reagent Grade:
2-Hydroxybenzoic Acid
C7H6O3 --- Formula Weight 138.12
CAS Number 69-72-7

REQUIREMENTS
Assay: 99.0% C7H6O3
Melting point: 158C-161C

MAXIMUM ALLOWABLE
Residue after ignition  0.01% maximum.
Chloride (Cl): 0.001% maximum.
Sulfate (SO4): 0.003% maximum.
Heavy metals (as Pb): 5 ppm maximum.
Iron (Fe): 2 ppm maximum.
Substances darkened by sulfuric acid: Passes test.

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Manufacturers

ANMOL CHEMICALS
Taloja Mumbai and Ankleshwar, INDIA
Representatives in Houston, Chicago and New York, USA
TEL: (OFF) +91 22 23726950, +91 22 23774610, +91 22 23723564

e-mail: info@anmol.org

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Last updated 25-nov-21

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Salicylic Acid
BP Ph Eur EP USP Analytical Reagent Grades Manufacturers
Salicylic Acid