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Riboflavin Sodium Phosphate or Riboflavin 5'-phosphate Sodium or Riboflavin 5′-Monophosphate Sodium Salt BP Ph Eur EP USP FCC Food Grade Manufacturers
Anmol Chemicals is a manufacturer supplier exporter of Riboflavin Sodium Phosphate or Riboflavin 5'-phosphate Sodium or Riboflavin 5′-Monophosphate Sodium Salt and it offers materials as per IP BP EP Ph Eur USP NF JP FCC Food Grade as per the the latest monograph at best prices. Anmol Chemicals Group, established in 1976, is the pioneer manufacturer of Specialty Chemicals, Pharmaceutical Excipients, Some API, Food Chemicals in India. Anmol Chemicals Group has manufacturing facilities spread across Western India, representatives in Houston, Chicago USA and Dubai, UAE. We also have toll manufacturing units for processing chemicals in a few countries around the world. We make IP, BP, EP, USP, NF, Ph. Eur., JP, FCC or Food Grade, Analytical Reagent Grade, LR or Laboratory Reagent Grades and Pure Grades of various chemicals. All our items are analyzed to meet the required standards. We can supply the product in grams for your laboratory trial and in tons for your plant scale jobs.
We manufacture Bulk Drugs / API, Excipients, Pharmaceuticals (IP BP USP NF Ph Eur EP JP), Specialty Chemicals (Pure/Reagent), Mineral Fortifiers (FCC). Our manufacturing facility is FDA approved and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) is available. Solid materials can be customized for particle size, shape, and bulk density. We observe WHO Good Manufacturing Practices and Good Laboratory Practices. We are a government-recognized STAR Export House and "Authorised Economic Operator (AEO)" per Indian Customs.
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Synonyms: Riboflavin Sodium Phosphate or Riboflavin 5'-phosphate Sodium or Riboflavin 5′-Monophosphate Sodium Salt
CAS Number: 130-40-5 or 6184-17-4, Molecular Weight: 514.4 or 478.33, Chemical Formula: C17H20N4NaO9P-2H2O or C17H20N4NaO9P, EINECS EC Number: 204-988-6 or 244-868-0, FEMA: ----,
General Properties and Specifications of Riboflavin Sodium Phosphate or Riboflavin 5'-phosphate Sodium or Riboflavin 5′-Monophosphate Sodium Salt:
Appearance: Yellow or orange-yellow, crystalline, hygroscopic powder.
Assay: 73.0 per cent to 79.0 per cent of riboflavin (C17H20N4O6; Mr 376.4) (dried substance).
Melting Point: 240C to 245C literature.
Solubility: Soluble in water.
Storage: Refrigerate. 2C to 8C. Hygroscopic.
Riboflavin 5′-Phosphate Sodium USP Grade Specifications:
C17H20N4NaO9P-2H2O --- 514.36
C17H20N4NaO9P --- 478.33
Riboflavin 5′-(dihydrogen phosphate), monosodium salt, dihydrate;
Riboflavine 5′-(sodium hydrogen phosphate), dihydrate
Anhydrous CAS 130-40-5
UNII: 957E53WV42
DEFINITION
Riboflavin 5′-Phosphate Sodium contains NLT the equivalent of 73.0% and NMT the equivalent of 79.0% of riboflavin (C17H20N4O6), calculated on the dried basis.
IDENTIFICATION
A. Color and Fluorescence of Solution:
Sample solution: 0.01 mg/mL in water
Analysis: Alternately expose to transmitted light and long-wavelength UV light.
Acceptance criteria: The solution is pale greenish yellow by transmitted light, and it exhibits an intense yellowish green fluorescence by reflected light under long-wavelength UV light that disappears upon the addition of mineral acids or alkalies.
B. Identification Tests: General, Sodium and Phosphate.
Free Phosphate: To pass the test by Ultraviolet-Visible Spectroscopy. --- NMT 1% as PO4.
Free Riboflavin and Riboflavin Diphosphates: To pass the test by chromatography.
Limit of Lumiflavin: To pass the test by Ultraviolet-Visible Spectroscopy.
Residue on Ignition: NMT 25.0%
Optical Rotation, Specific Rotation:
Sample solution: 15 mg/mL in 5 N hydrochloric acid. Use the solution within 15 min.
Acceptance criteria: +37.0° to +42.0°
pH: 10 mg/mL solution. Acceptance criteria: 5.0–6.5
Loss on Drying Dry a sample under vacuum over phosphorus pentoxide at 100C for 5 h: it loses NMT 7.5% of its weight.
Packaging and Storage: Preserve in tight, light-resistant containers.
Riboflavin Sodium Phosphate BP Ph Eur Grade Specifications:
C17H20N4NaO9P --- 478.3 CAS 130-40-5
Action and use: Vitamin B2.
DEFINITION
Mixture containing riboflavin 5′-(sodium hydrogen phosphate) as the main component and other riboflavin sodium monophosphates.
Content: 73.0 per cent to 79.0 per cent of riboflavin (C17H20N4O6; Mr 376.4) (dried substance). It contains a variable quantity of water.
CHARACTERS
Appearance: Yellow or orange-yellow, crystalline, hygroscopic powder.
Solubility: Soluble in water, very slightly soluble in ethanol (96 per cent).
IDENTIFICATION
A. Ultraviolet and visible absorption spectrophotometry.
B. Examine the chromatograms.
C. Dissolve about 10 mg in dilute sodium hydroxide solution and dilute to 100 mL with the same solution. Expose 1 mL of this solution to ultraviolet light at 254 nm for 5 min, add sufficient acetic acid to make the solution acidic to blue litmus paper and shake with 2 mL of methylene chloride. The lower layer shows yellow fluorescence.
TESTS
pH: 5.0 to 6.5
Specific optical rotation: + 38.0 to + 43.0 (dried substance).
Dissolve 0.300 g in 18.2 mL of hydrochloric acid and dilute to 25.0 mL with water.
Impurity E: To about 35 mg add 10 mL of methylene chloride, shake for 5 min and filter. The filtrate is not more intensely coloured than reference solution.
Related substances: To pass the test by Liquid chromatography.
Inorganic phosphate: Maximum 1.5 per cent.
Storage: In an airtight container, protected from light.
Riboflavin 5-Phosphate Sodium FCC Food Grade:
Flavin Mononucleotide, Sodium Salt; Riboflavin 5′-Phosphate Ester Monosodium Salt; Riboflavin 5′-Phosphate Ester Monosodium Salt, Dihydrate.
C17H20N4NaO9P-2H2O Formula weight 514.36>
INS: 101(ii) CAS: 130-40-5
DESCRIPTION
Riboflavin 5′-Phosphate Sodium occurs as a fine, orange-yellow, crystalline powder. One-gram dissolves in about 30 mL of water. When dry, it is not affected by diffused light, but when in solution, light induces deterioration rapidly. It is hygroscopic.
Function: Nutrient.
REQUIREMENTS
Identification: A 1.5:100 (w/v) aqueous solution responds to the Identification Test in the monograph for Riboflavin.
Assay: Not less than the equivalent of 73.0% and not more than the equivalent of 79.0% of riboflavin (C17H20N4O6), calculated on the dried basis.
Free Phosphate: Not more than 1.0%, calculated as PO4.
Free Riboflavin: Not more than 6.0%, calculated on the dried basis.
Lead: Not more than 2 mg/kg.
Loss on Drying: Not more than 7.5%.
Optical (Specific) Rotation [α]D25°: Between +37.0° and +42.0°, calculated on the dried basis.
pH of a 1:100 Solution: Between 5.0 and 6.5
Residue on Ignition: Not more than 25.0%.
Riboflavin Diphosphate: Not more than 6.0% as riboflavin (C17H20N4O6), calculated on the dried basis.
Riboflavin Sodium Phosphate or Riboflavin 5'-phosphate Sodium or Riboflavin 5′-Monophosphate Sodium Salt is found in BP Ph Eur EP JP IP USP FCC Food Grade monographs.
Keywords: Riboflavin Sodium Phosphate or Riboflavin 5'-phosphate Sodium or Riboflavin 5′-Monophosphate Sodium Salt IP BP Ph Eur EP USP Analytical Reagent FCC Food Grade CAS Number 130-40-5 or 6184-17-4 Manufacturer Supplier Exporter Monograph Uses Chemical Molecular Formula Weight.
Manufacturer Supplier Exporter
ANMOL CHEMICALS Private Limited
Representatives in Houston, Chicago and New York, USA
TEL: (OFF) +91 22 23726950, +91 22 23774610, +91 22 23723564
Taloja Navi Mumbai, Banglore, INDIA
e-mail: info@anmol.org
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Last updated 7-jan-26
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Riboflavin Sodium Phosphate
Riboflavin 5'-phosphate Sodium or Riboflavin 5′-Monophosphate Sodium Salt EP BP Ph Eur USP FCC Food Grade Manufacturers