(FDA) GMP Approved, ISO-9001:2008, ISO-14001, ISO OHSAS-18001, HACCP, FSSC 220000, FSSAI, "REACH" Pre-registered Kosher & Halal Certified
Potassium Hydrogen Aspartate Hemihydrate BP IP Grade Manufacturers
Anmol Chemicals Group, established in 1976, is the pioneer manufacturer of Specialty chemicals, Pharmaceutical Excipients, Fragrance & Flavor chemicals in India. Anmol Chemicals Group has manufacturing facilities spread across Western India, representatives in Houston Chicago USA and toll manufacturers in China. We also have toll manufacturing units for processing chemicals in a few countries around the world. We make IP, BP, USP, Ph. Eur., FCC or Food Grade, ACS, AR or Analytical Reagent Grade, LR or Laboratory Reagent Grade, Pure and Technical Grades of various chemicals. All our items are analyzed to meet the required standards.
Our manufacturing facility is FDA approved and GMP, ISO-9001-2008, ISO-14001, ISO OHSAS 18000, ISO 22000-2005 HACCP, FSSAI, FSSC-22000, certified. We are offering products manufactured as per Kosher and Halal approved certified method. We are pre-registered with "Reach" for export to European countries. We can give all solid chemical materials as per specified size or shape.
Potassium Hydrogen Aspartate Hemihydrate SDS of Manufacturers
Synonyms: Aspartic acid potassium salt hemihydrate, Potassium hydrogen (2S)-2-aminobutanedioate hemihydrate
CAS Number: 7259-25-8, Molecular Weight: 180, Chemical Formula: C4H6KNO4(H2O)0.5, EINECS EC Number: ----, FEMA: ----,
Potassium Hydrogen Aspartate Hemihydrate BP Grade
C4H6KNO4,½H2O -- 180.2
Potassium hydrogen (2S)-2-aminobutanedioate hemihydrate.
Content: 99.0 per cent to 101.0 per cent (anhydrous substance).
Appearance: White or almost white, powder or crystalline powder, or colourless crystals.
Solubility: Very soluble in water, practically insoluble in alcohol and in methylene chloride.
A. It complies with the test for specific optical rotation (see Tests).
B. Examine the chromatograms obtained in the test for ninhydrin-positive substances.
Results: The principal spot in the chromatogram obtained with test solution (b) is similar in position, colour and size to the principal spot in the chromatogram obtained with reference solution (a).
C. It gives reaction (b) of potassium (2.3.1).
Solution S: Dissolve 2.5 g in carbon dioxide-free water prepared from distilled water and dilute to 100 ml with the same solvent.
Appearance of solution: Solution S is clear and colourless.
pH: 6.0 to 7.5 for solution S.
Specific optical rotation: + 18.0 to + 20.5 (anhydrous substance).
Dissolve 0.50 g in a mixture of equal volumes of hydrochloric acid and water and dilute to 25.0 ml with the same mixture of solvents.
Ninhydrin-positive substances: Thin-layer chromatography.
Test solution (a): Solution S.
Test solution (b): Dilute 1.0 ml of solution S to 10.0 ml with water.
Reference solution (a): Dissolve 25 mg of potassium hydrogen aspartate hemihydrate CRS in water and dilute to 10 ml with the same solvent.
Reference solution (b): Dilute 1.0 ml of test solution (b) to 20.0 ml with water R.
Reference solution (c): Dissolve 10 mg of glutamic acid CRS and 10 mg of the substance to be examined in water and dilute to 25 ml with the same solvent.
Plate: TLC silica gel plate R.
Mobile phase: glacial acetic acid R, water R, butanol R (20:20:60 V/V/V).
Application: 5 Î¼l.
Development: Over 2/3 of the plate.
Drying: In air.
Detection: Spray with ninhydrin solution and heat at 100-105C for 15 min.
System suitability: Reference solution (c):
the chromatogram shows 2 clearly separated principal spots.
Limits: Test solution (a):
any impurity: any spot, apart from the principal spot, is not more intense than the spot in the chromatogram obtained with reference solution (b) (0.5 per cent).
Chlorides: Maximum 200 ppm.
Sulphates: Maximum 500 ppm.
Ammonium: Maximum 200 ppm, determined on 50 mg.
Iron: Maximum 30 ppm.
Heavy metals: Maximum 10 ppm.
Water: 4.0 per cent to 6.0 per cent, determined on 0.200 g.
Taloja Mumbai and Ankleshwar Gujarat, INDIA
Representatives in Houston, Chicago and New York, USA
TEL: (OFF) 91-22-23726950, 23774610, 23723564
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Last updated 7-aug-17
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Representatives in New York, Houston - Texas, Chicago - Illinois, Los Angeles.
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Potassium Hydrogen Aspartate Hemihydrate
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