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Carboxymethylcellulose Calcium USP Carmellose Calcium BP Ph Eur IP Manufacturers
Anmol Chemicals is a manufacturer supplier exporter of Carboxymethylcellulose Calcium, Carmellose Calcium and it offers materials as per IP BP EP Ph Eur USP NF JP FCC Food Grade as per the the latest monograph at best prices. Anmol Chemicals Group, established in 1976, is the pioneer manufacturer of Specialty Chemicals, Pharmaceutical Excipients, Some API, Food Chemicals in India. Anmol Chemicals Group has manufacturing facilities spread across Western India, representatives in Houston, Chicago USA and Dubai, UAE. We also have toll manufacturing units for processing chemicals in a few countries around the world. We make IP, BP, EP, USP, NF, Ph. Eur., JP, FCC or Food Grade, Analytical Reagent Grade, LR or Laboratory Reagent Grades and Pure Grades of various chemicals. All our items are analyzed to meet the required standards. We can supply the product in grams for your laboratory trial and in tons for your plant scale jobs.
We manufacture Bulk Drugs / API, Excipients, Pharmaceuticals (IP BP USP NF Ph Eur EP JP), Specialty Chemicals (Pure/Reagent), Mineral Fortifiers (FCC). Our manufacturing facility is FDA approved and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) is available. Solid materials can be customized for particle size, shape, and bulk density. We observe WHO Good Manufacturing Practices and Good Laboratory Practices. We are a government-recognized STAR Export House and "Authorised Economic Operator (AEO)" per Indian Customs.
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Carmellose Calcium or Carboxymethylcellulose Calcium SDS of Manufacturers
Synonyms: Calcium salt of a partly O-carboxymethylated cellulose, Carboxymethylcellulose Calcium
CAS Number: 9050-04-8, Molecular Weight: ----, Chemical Formula: ----, EINECS EC Number: 618-566-8, FEMA: ----,
Carmellose Calcium BP Ph Eur Grade Specifications
Ph Eur --- CAS 9050-04-8
Action and use: Excipient in pharmaceutical products; bulk laxative.
Calcium salt of a partly O-carboxymethylated cellulose.
Appearance: White or yellowish-white powder, hygroscopic after drying.
Solubility: Practically insoluble in acetone, in alcohol and in toluene. It swells with water to form a suspension.
A. Shake 0.1 g thoroughly with 10 ml of water. Add 2 ml of dilute sodium hydroxide solution and allow to stand for 10 min (solution A). Dilute 1 ml of solution A to 5 ml with water. To 0.05 ml add 0.5 ml of a 0.5 g/l solution of chromotropic acid, sodium salt in a 75 per cent m/m solution of sulphuric acid and heat on a water-bath for 10 min. A reddish-violet colour develops.
B. Shake 5 ml of solution A obtained in identification test A with 10 ml of acetone. A white, flocculent precipitate is produced.
C. Shake 5 ml of solution A obtained in identification test A with 1 ml of ferric chloride solution. A brown, flocculent precipitate is formed.
D. Ignite 1 g and dissolve the residue in a mixture of 5 ml of acetic acid and 10 ml of water. Filter if necessary and boil the filtrate for a few minutes. Cool and neutralise with dilute ammonia. The solution gives reaction of calcium.
Solution S: Shake 1.0 g with 50 ml of distilled water, add 5 ml of dilute sodium hydroxide solution and dilute to 100 ml with distilled water.
Alkalinity: Shake 1.0 g thoroughly with 50 ml of carbon dioxide-free water and add 0.05 ml of phenolphthalein solution R . No red colour develops.
Chlorides: Maximum 0.36 per cent.
Sulphates: Maximum 1 per cent.
Heavy metals: Maximum 20 ppm.
Loss on drying: Maximum 10.0 per cent, determined on 1.000 g by drying in an oven at 105C for 4 h.
Sulphated ash: 10.0 per cent to 20.0 per cent, determined on 1.0 g in a platinum crucible.
Carboxymethylcellulose Calcium USP Grade Specifications:
Cellulose, carboxymethyl ether, calcium salt;
Cellulose carboxymethyl ether calcium salt CAS 9050-04-8
Carboxymethylcellulose Calcium is the calcium salt of a polycarboxymethyl ether of cellulose.
IDENTIFICATIONResidue on Ignition: 10.0%–20.0%; use 1.0 g, previously dried.
Sample solution: Shake thoroughly 0.1 g of Carboxymethylcellulose Calcium with 10 mL of water, followed by 2 mL of 1 N sodium hydroxide, and allow to stand for 10 min. [Note— Save the unused portion of the Sample solution for use in Identification tests B and C.]
Analysis: To 1 mL of the Sample solution add water to make 5 mL. To 1 drop of the resulting solution, add 0.5 mL of chromotropic acid, and heat in a water bath for 10 min.
Acceptance criteria: A red-purple color develops.
Analysis: Shake 5 mL of the Sample solution prepared in Identification test A with 10 mL of acetone.
Acceptance criteria: A white, flocculent precipitate is formed.
Analysis: Shake 5 mL of the Sample solution prepared in Identification test A with 1 mL of ferric chloride.
Acceptance criteria: A brown, flocculent precipitate is formed.
D. Identification Tests—General:
Analysis: Ignite 1 g to ash, dissolve the residue in 10 mL of water and 5 mL of 6 N acetic acid, and filter, if necessary. Boil the filtrate, cool, and neutralize with 6 N ammonium hydroxide.
Acceptance criteria: Meets the requirements.
Chloride and Sulfate: To pass the test.
Chloride and Sulfate: To pass the test.
Alkalinity: Shake thoroughly 1.0 g with 50 mL of freshly boiled and cooled water and add 2 drops of phenolphthalein: no red color develops.
Loss on Drying: Dry a sample at 105C for 4 h: it loses NMT 10.0% of its weight.
Keywords: Calcium salt of a partly O-carboxymethylated cellulose, Carboxymethylcellulose Calcium, Carmellose Calcium IP BP Ph Eur EP USP Analytical Reagent FCC Food Grade Manufacturer Supplier Exporter Monograph Uses Chemical Molecular Formula Weight.
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Last updated 13-aug-23
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Carboxymethylcellulose Calcium USP IP BP Ph Eur Grades Manufacturers