Calcium Folinate BP Ph Eur Grade Manufacturers

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Calcium Folinate BP Ph Eur Grade Manufacturers

Anmol Chemicals is a manufacturer supplier exporter of Calcium Folinate and it offers materials as per IP BP EP Ph Eur USP NF JP FCC Food Grade as per the the latest monograph at best prices. Anmol Chemicals Group, established in 1976, is the pioneer manufacturer of Specialty Chemicals, Pharmaceutical Excipients, Some API, Food Chemicals in India. Anmol Chemicals Group has manufacturing facilities spread across Western India, representatives in Houston, Chicago USA and Dubai, UAE. We also have toll manufacturing units for processing chemicals in a few countries around the world. We make IP, BP, EP, USP, NF, Ph. Eur., JP, FCC or Food Grade, Analytical Reagent Grade, LR or Laboratory Reagent Grades and Pure Grades of various chemicals. All our items are analyzed to meet the required standards. We can supply the product in grams for your laboratory trial and in tons for your plant scale jobs.

We manufacture Bulk Drugs / API, Excipients, Pharmaceuticals (IP BP USP NF Ph Eur EP JP), Specialty Chemicals (Pure/Reagent), Mineral Fortifiers (FCC). Our manufacturing facility is FDA approved and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) is available. Solid materials can be customized for particle size, shape, and bulk density. We observe WHO Good Manufacturing Practices and Good Laboratory Practices. We are a government-recognized STAR Export House and "Authorised Economic Operator (AEO)" per Indian Customs.

Synonyms: Calcium Folinate
CAS Number: 1492-18-8 (anhydrous), Molecular Weight: 511.50 (anhydrous), Chemical Formula: C20H21CaN7O7-xH2O

Calcium Folinate BP Ph Eur Grade Specifications
Ph Eur
C20H21CaN7O7,xH2O --- 511.5 --- 1492-18-8
Action and use: Antidote to folic acid antagonists.

DEFINITION
Calcium (2S)-2-[[4-[[[(6RS)-2-amino-5-formyl-4-oxo1,4,5,6,7,8-hexahydropteridin-6-yl]methyl]amino]benzoyl]amino]pentanedioate.
Content:
calcium folinate (C20H21CaN7O7): 97.0 per cent to 102.0 per cent (anhydrous substance);
calcium (Ca; A r 40.08): 7.54 per cent to 8.14 per cent (anhydrous substance). It contains a variable amount of water.

CHARACTERS
Appearance: White or light yellow, amorphous or crystalline powder.
Solubility: Sparingly soluble in water, practically insoluble in acetone and in ethanol (96 per cent). The amorphous form may produce supersaturated solutions in water.

IDENTIFICATION
First identification A, B, D.
Second identification A, C, D.
A. Specific optical rotation.
B. Infrared absorption spectrophotometry.
C. Thin-layer chromatography.
D. It gives reaction of calcium.
Carry out the tests and the assay as rapidly as possible, protected from actinic light.

TESTS
Solution S: Dissolve 1.25 g in carbon dioxide-free water, heating at 40C if necessary, and dilute to 50.0 ml with the same solvent.
Appearance of solution: Solution S is clear and its absorbance at 420 nm is not greater than 0.60.
pH: 6.8 to 8.0 for solution S.
Specific optical rotation: + 14.4 to + 18.0 (anhydrous substance), determined on solution S.
Acetone, ethanol and methanol Limits:
acetone: maximum 0.5 per cent;
ethanol: maximum 3.0 per cent;
methanol: maximum 0.5 per cent.
Related substances: To pass the test,
Chlorides: Maximum 0.5 per cent.
Heavy metals: Maximum 50 ppm.
Platinum: Maximum 20.0 ppm.
Water: Maximum 17.0 per cent, determined on 0.200 g (ground to a very fine powder ).
Bacterial endotoxins: Less than 0.5 IU/mg, if intended for use in the manufacture of parenteral dosage forms without a further appropriate procedure for the removal of bacterial endotoxins.

STORAGE
In an airtight container, protected from light. If the substance is sterile, store in a sterile, airtight, tamper-proof container .

Keywords: Calcium Folinate IP BP Ph Eur EP USP Analytical Reagent FCC Food Grade CAS Number 1492-18-8 (anhydrous) Manufacturer Supplier Exporter Monograph Uses Chemical Molecular Formula Weight.

ANMOL CHEMICALS
Now maturing as Anmol Chemicals Private Limited
Representatives in Houston, Chicago and New York, USA
TEL: (OFF) +91 22 23726950, +91 22 23774610, +91 22 23723564
Taloja Navi Mumbai, INDIA

Exporters to USA, Canada, UAE, Kuwait, Qatar, Gautemala, Tunisia, Europe, South Africa, Bangladesh, Sri Lanka, Tanzania, Kenya, Egypt, Iraq, Turkey, Israel, Vietnam, Nigeria, Uganda, Brazil, Chile, Argentina, Dubai, UAE, Saudi Arabia, Cameroon, Mexico, Brazil, Chile, Argentina, Korea, Thailand, Malaysia, Indonesia, Jakarta, Australia, China, Germany, France, etc.

Representatives in New York, Houston - Texas, Chicago - Illinois, Los Angeles.

All products are Sold for Industrial and Laboratory Use only. No other use is permitted.