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Riboflavin or Vitamin B2 USP BP Ph Eur FCC Food Grade Manufacturers
Anmol Chemicals is a manufacturer supplier exporter of Riboflavin or Vitamin B2 and it offers materials as per IP BP EP Ph Eur USP NF JP FCC Food Grade as per the the latest monograph at best prices. Anmol Chemicals Group, established in 1976, is the pioneer manufacturer of Specialty Chemicals, Pharmaceutical Excipients, Some API, Food Chemicals in India. Anmol Chemicals Group has manufacturing facilities spread across Western India, representatives in Houston, Chicago USA and Dubai, UAE. We also have toll manufacturing units for processing chemicals in a few countries around the world. We make IP, BP, EP, USP, NF, Ph. Eur., JP, FCC or Food Grade, Analytical Reagent Grade, LR or Laboratory Reagent Grades and Pure Grades of various chemicals. All our items are analyzed to meet the required standards. We can supply the product in grams for your laboratory trial and in tons for your plant scale jobs.
We manufacture Bulk Drugs / API, Excipients, Pharmaceuticals (IP BP USP NF Ph Eur EP JP), Specialty Chemicals (Pure/Reagent), Mineral Fortifiers (FCC). Our manufacturing facility is FDA approved and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) is available. Solid materials can be customized for particle size, shape, and bulk density. We observe WHO Good Manufacturing Practices and Good Laboratory Practices. We are a government-recognized STAR Export House and "Authorised Economic Operator (AEO)" per Indian Customs.
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Riboflavin or Vitamin B2 SDS of Manufacturers
Synonyms: Riboflavin or Vitamin B2
CAS Number: 83-88-5, Molecular Weight: 376.36, Chemical Formula: C17H20N4O6, EINECS EC Number: 201-507-1, FEMA: ----,
Riboflavin, also known as vitamin B2, is a vitamin found in food and sold as a dietary supplement. Riboflavin or Vitamin B2 is one of the B vitamins, which are all water soluble. Riboflavin is naturally present in some foods, added to some food products, and available as a dietary supplement. In foods it has an E number of E101, E101(iii)
General Properties and Specifications of Riboflavin or Vitamin B2:
Appearance: Orange yellow crystalline powder.
Solubility of 2% solution in 0.5N NaOH: Clear orange.
Assay: 98% minimum.
Loss on drying: 1.5% maximum.
Sulfated Ash: 0.1% maximum.
pH: 5.5 - 7.2 for 0.07 g/l in water @ 20C.
Relative Density: 1.65 (Predicted).
Melting Point: 280C to 290C literature.
Boiling Point: 710C (Predicted).
Solubility: Very slightly soluble in water.
Suitability for Cell Culture: Passes.
Bacterial Endotoxin Test (BET) (EU/mg = IU/mg): <0.05 EU/mg.
Storage: Room temperature. Preferably refrigerate. In a light resistance container.
Riboflavin USP Grade Specifications:
C17H20N4O6 376.36
Riboflavine CAS 83-88-5
UNII: TLM2976OFR
DEFINITION
Riboflavin contains NLT 98.0% and NMT 102.0% of riboflavin (C17H20N4O6), calculated on the dried basis.
IDENTIFICATION
A. Color and Fluorescence of Solution:
Sample solution: 0.01 mg/mL in water
Analysis: Alternately expose to transmitted light and long-wavelength UV light.
Acceptance criteria: The Sample solution is pale greenish yellow by transmitted light. By reflected light, it exhibits an intense yellowish-green fluorescence that disappears upon the addition of mineral acids or alkalies.
Residue on Ignition: NMT 0.3%
Limit of Lumiflavin: To pass the test.
Optical Rotation, Specific Rotation:
Sample solution: 5 mg/mL in 0.05 M carbonate-free sodium hydroxide.
Analysis: Measure the specific rotation within 30 min of preparation.
Acceptance criteria: −115° to −135°
Loss on Drying: Dry 500 mg at 105C for 2 h. It loses NMT 1.5% of its weight.
Riboflavin BP Ph Eur Grade Specifications:
C17H20N4O6 --- 376.4 CAS 83-88-5
Action and use: Vitamin B2.
DEFINITION
7,8-Dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]benzo[g]pteridine-2,4(3H,10H)-dione.
This monograph applies to riboflavin produced by fermentation.
Content: 97.0 per cent to 103.0 per cent (dried substance).
CHARACTERS
Appearance: Yellow or orange-yellow, crystalline powder.
Solubility: Very slightly soluble in water, practically insoluble in ethanol (96 per cent).
Solutions deteriorate on exposure to light, especially in the presence of alkali.It shows polymorphism.
IDENTIFICATION
A. Specific optical rotation.
B. Thin-layer chromatography.
C. Dissolve about 1 mg in 100 mL of water. The solution has, by transmitted light, a pale greenish yellow colour, and, by reflected light, an intense yellowish-green fluorescence which disappears on the addition of mineral acids or alkalis.
Specific optical rotation: -115 to -135 (dried substance).
Dissolve 50.0 mg in 0.05 M sodium hydroxide free from carbonate and dilute to 10.0 mL with the same alkaline solution. Measure the optical rotation within 30 min of dissolution.
Absorbance:
Test solution Dilute the final solution prepared for the assay with an equal volume of water.
Absorption maxima at 223 nm, 267 nm, 373 nm and 444 nm.
Absorbance ratios:
— A373/A267 = 0.31 to 0.33;
— A444/A267 = 0.36 to 0.39.
Related substances: To pass the test.
Loss on drying: Maximum 1.5 per cent, determined on 1.000 g by drying in an oven at 105C.
Sulfated ash: Maximum 0.1 per cent, determined on the residue obtained in the test for loss on drying.
Riboflavin FCC Food Grade Specifications:
Vitamin B2
C17H20N4O6 Formula weight 376.37
INS: 101(i) CAS 83-88-5
DESCRIPTION
Riboflavin occurs as a yellow to orange-yellow, crystalline powder. When dry, it is not affected by diffused light, but when in solution, light induces deterioration. It melts at about 280C with decomposition, and its saturated solution is neutral to litmus. One-gram dissolves in 3000 to about 20,000 mL of water, the variations being due to differences in the internal crystalline structure. It is less soluble in alcohol than in water. It is insoluble in ether and in chloroform, but it is very soluble in dilute solutions of alkalis.
Function: Nutrient.
Identification: A solution of 1 mg of sample in 100 mL of water is pale green-yellow by transmitted light and has an intense yellow-green fluorescence that disappears on the addition of mineral acids or alkalies.
Assay: Not less than 98.0% and not more than 102.0% of C17H20N4O6, calculated on the dried basis.
Loss on Drying: Not more than 1.5%.
Lumiflavin: Passes test.
Optical (Specific) Rotation: [α]D25°: Between +56.5° and +59.5°, calculated on the dried basis.
Residue on Ignition: Not more than 0.3%.
Keywords: Riboflavin or Vitamin B2 IP BP Ph Eur EP USP Analytical Reagent FCC Food Grade CAS Number 83-88-5 Manufacturer Supplier Exporter Monograph Uses Chemical Molecular Formula Weight.
Manufacturer Supplier Exporter
ANMOL CHEMICALS
Now maturing as Anmol Chemicals Private Limited
Representatives in Houston, Chicago and New York, USA
TEL: (OFF) +91 22 23726950, +91 22 23774610, +91 22 23723564
Taloja Navi Mumbai, INDIA
e-mail: info@anmol.org
Copyright and Usual Disclaimer is Applicable
Last updated
26-mar-24
Exporters to USA, Canada, UAE, Kuwait, Qatar, Gautemala, Tunisia, Europe, South Africa, Bangladesh, Sri Lanka, Tanzania, Kenya, Egypt, Iraq, Turkey, Israel, Vietnam, Nigeria, Uganda, Brazil, Chile, Argentina, Dubai, UAE, Saudi Arabia, Cameroon, Mexico, Brazil, Chile, Argentina, Korea, Thailand, Malaysia, Indonesia, Jakarta, Australia, China, Germany, France, etc.
Representatives in New York, Houston - Texas, Chicago - Illinois, Los Angeles.
All products are Sold for Industrial and Laboratory Use only. No other use is permitted.
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Riboflavin
Vitamin B2 BP Ph Eur USP FCC Food Grades Manufacturers