Polyoxyl 40 Hydrogenated Castor Oil BP Ph Eur USP NF Manufacturers

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Polyoxyl 40 Hydrogenated Castor Oil or Macrogolglycerol Hydroxystearate USP NF BP Ph Eur Grade Manufacturers

Anmol Chemicals is a manufacturer supplier exporter of Polyoxyl 40 Hydrogenated Castor Oil or Macrogolglycerol Hydroxystearate and it offers materials as per IP BP EP Ph Eur USP NF JP FCC Food Grade as per the the latest monograph at best prices. Anmol Chemicals Group, established in 1976, is the pioneer manufacturer of Specialty Chemicals, Pharmaceutical Excipients, Some API, Food Chemicals in India. Anmol Chemicals Group has manufacturing facilities spread across Western India, representatives in Houston, Chicago USA and Dubai, UAE. We also have toll manufacturing units for processing chemicals in a few countries around the world. We make IP, BP, EP, USP, NF, Ph. Eur., JP, FCC or Food Grade, Analytical Reagent Grade, LR or Laboratory Reagent Grades and Pure Grades of various chemicals. All our items are analyzed to meet the required standards. We can supply the product in grams for your laboratory trial and in tons for your plant scale jobs.

We manufacture Bulk Drugs / API, Excipients, Pharmaceuticals (IP BP USP NF Ph Eur EP JP), Specialty Chemicals (Pure/Reagent), Mineral Fortifiers (FCC). Our manufacturing facility is FDA approved and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) is available. Solid materials can be customized for particle size, shape, and bulk density. We observe WHO Good Manufacturing Practices and Good Laboratory Practices. We are a government-recognized STAR Export House and "Authorised Economic Operator (AEO)" per Indian Customs.

Synonyms: Polyoxyl 40 Hydrogenated Castor Oil or Macrogolglycerol Hydroxystearate
CAS Number: 61788-85-0, EINECS EC Number: 500-147-5, FEMA: ----,

General Properties and Specifications of Polyoxyl 40 Hydrogenated Castor Oil or Macrogolglycerol Hydroxystearate:
Appearance: White to pale yellow paste at 20C and oily at 30C+.
Odor: Almost Odorless.
Flash point: 242C.
Solubility: > 490 g/L in water at 23C. Soluble in ethanol.
Acid value: < 0.8 mg KOH/g.

DEFINITION
Polyoxyl 40 Hydrogenated Castor Oil contains mainly the tri-hydroxystearate ester of ethoxylated glycerol, with smaller amounts of polyethylene glycol tri-hydroxystearate and of the corresponding free glycols. It results from the reaction of glycerol tri-hydroxystearate with 40 to 45 moles of ethylene oxide.

IDENTIFICATION
A.
Sample: 0.1 g
Analysis: Dissolve the Sample in 1 mL of water, add 9 mL of sodium chloride solution (50 mg/mL), and heat in a water bath.
Acceptance criteria: The solution becomes turbid at 70C to 85C.
B.
Sample: 0.1 g
Analysis: Dissolve the Sample in 10 mL of alcoholic potassium hydroxide TS, boil for 3 min, and evaporate to dryness. Mix the residue with 5 mL of water.
Acceptance criteria: The residue dissolves, yielding a clear solution. Add a few drops of glacial acetic acid. A white precipitate is formed.
Residue on Ignition: NMT 0.3%
Congealing Temperature: 16C to 26C
Fats and Fixed Oils: NMT 2.0
Fats and Fixed Oils, Hydroxyl Value: 60 to 80
Fats and Fixed Oils, Iodine Value: NMT 2.0
Fats and Fixed Oils, Saponification Value: 45 to 69
Water Determination: NMT 3.0%
Packaging and Storage: Preserve in tight containers.

Specifications of Hydrogenated Polyoxyl Castor Oil BP Ph Eur Grade:
Macrogolglycerol Hydroxystearate, Ph. Eur.

DEFINITION
Contains mainly tris(12-hydroxystearyl) glycerol ethoxylated with 7 to 60 molecules of ethylene oxide (nominal value), with small amounts of macrogol hydroxystearate and of the corresponding free glycols. It results from the reaction of hydrogenated castor oil with ethylene oxide.

CHARACTERS
Appearance:
— if less than 10 units of ethylene oxide per molecule: yellowish, turbid, viscous liquid;
— if more than 20 units of ethylene oxide per molecule: white or yellowish semi-liquid or pasty mass.
Solubility:
— if less than 10 units of ethylene oxide per molecule: practically insoluble in water, soluble in acetone, dispersible in ethanol (96 per cent);
— if more than 20 units of ethylene oxide per molecule: freely soluble in water, in acetone and in ethanol (96 per cent), practically insoluble in light petroleum.

IDENTIFICATION
A. Iodine value.
B. Saponification value.
C. Thin-layer chromatography. To pass the test.
Results: The principal spot in the chromatogram obtained with the test solution is similar in position and colour to the principal spot in the chromatogram obtained with the reference solution.
D. Place about 2 g in a test-tube and add 0.2 mL of sulfuric acid. Close the tube using a stopper fitted with a glass tube bent twice at right angles. Heat the tube until white fumes appear. Collect the fumes in 1 mL of mercuric chloride solution. A white precipitate is formed and the fumes turn a filter paper impregnated with alkaline potassium tetraiodomercurate solution black.

TESTS
Solution S: Dissolve 5.0 g of macrogolglycerol hydroxystearate with less than 40 units of ethylene oxide per molecule in a mixture of 50 volumes of acetone and 50 volumes of anhydrous ethanol and dilute to 50 mL with the same mixture of solvents.

Dissolve 5.0 g of macrogolglycerol hydroxystearate with 40 units or more of ethylene oxide per molecule in carbon dioxide-free water and dilute to 50 mL with the same solvent.

Appearance of solution: Solution S is not more opalescent than reference suspension III and not more intensely coloured than reference solution.
Alkalinity: To 2 mL of solution S add 0.5 mL of bromothymol blue solution. The solution is not blue.
Acid value: Maximum 2.0, determined on 5.0 g.
Hydroxyl value: To pass the test.
Iodine value: Maximum 5.0.
Saponification value: To pass the test.
Residual ethylene oxide and dioxan: Maximum 1 ppm of residual ethylene oxide and 10 ppm of residual dioxan.
Water: Maximum 3.0 per cent, determined on 2.000 g.
Total ash: Maximum 0.3 per cent, determined on 2.0 g.

Keywords: Polyoxyl 40 Hydrogenated Castor Oil or Macrogolglycerol Hydroxystearate IP BP Ph Eur EP USP Analytical Reagent FCC Food Grade Manufacturer Supplier Exporter Monograph Uses Chemical Molecular Formula Weight.

ANMOL CHEMICALS
Now maturing as Anmol Chemicals Private Limited
Representatives in Houston, Chicago and New York, USA
TEL: (OFF) +91 22 23726950, +91 22 23774610, +91 22 23723564
Taloja Navi Mumbai, INDIA

Exporters to USA, Canada, UAE, Kuwait, Qatar, Gautemala, Tunisia, Europe, South Africa, Bangladesh, Sri Lanka, Tanzania, Kenya, Egypt, Iraq, Turkey, Israel, Vietnam, Nigeria, Uganda, Brazil, Chile, Argentina, Dubai, UAE, Saudi Arabia, Cameroon, Mexico, Brazil, Chile, Argentina, Korea, Thailand, Malaysia, Indonesia, Jakarta, Australia, China, Germany, France, etc.

Representatives in New York, Houston - Texas, Chicago - Illinois, Los Angeles.

All products are Sold for Industrial and Laboratory Use only. No other use is permitted.

Polyoxyl 40 Hydrogenated Castor Oil
Macrogolglycerol Hydroxystearate BP Ph Eur USP NF Grades Manufacturers