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Edetate Disodium EDTA Disodium Edetate USP BP Ph Eur IP FCC Food Grade Manufacturers
Anmol Chemicals Group, established in 1976, is the pioneer manufacturer of Specialty chemicals, Pharmaceutical Excipients, Fragrance & Flavor chemicals in India. Anmol Chemicals Group has manufacturing facilities spread across Western India, representatives in Houston Chicago USA, Dubai and UAE. We also have toll manufacturing units for processing chemicals in a few countries around the world. We make IP, BP, USP, Ph. Eur., FCC or Food Grade, Analytical Reagent Grade, LR or Laboratory Reagent Grade, Pure and Technical Grades of various chemicals. All our items are analyzed to meet the required standards. We can supply the material in grams for your laboratory trial and in tons for your plant scale jobs.
Our manufacturing facility is FDA approved and cGMP, GLP (FDA) Approved, ISO 9001, ISO 14001, ISO 17025, ISO 45001, ISO 22000, HACCP, FSSAI, FSSC 22000, Halal and Kosher certified. We are registered with "REACH" for export to European countries. Solid materials can be customized for particle size, shape and bulk density. We observe WHO Good Manufacturing Practice and Good Laboratory Practice. We are a STAR Export House and “Authorised Economic Operator” as per Indian customs.
Edetate Disodium EDTA Disodium Edetate SDS of Manufacturers
Synonyms: Edetate Disodium, Disodium EDTA, Disodium Edetate
CAS Number: 139-33-3, Molecular Weight: 372.2, Chemical Formula: C10H14N2O8.2H2O, EINECS EC Number: 205-358-3, FEMA: ----,
Edetate Disodium USP
C10H14N2Na2O8-2H2O --- 372.24
Glycine, N,N′-1,2-ethanediylbis[N-(carboxymethyl)-, disodium salt, dihydrate.
Disodium (ethylenedinitrilo)tetraacetate dihydrate [CAS 6381-92-6].
Anhydrous 336.21 [CAS 139-33-3].
Edetate Disodium contains not less than 99.0 percent and not more than 101.0 percent of C10H14N2Na2O8, calculated on the dried basis.
A: Infrared Absorption 197K : un-dried.
B: To 5 mL of water in a test tube add 2 drops of ammonium thiocyanate TS and 2 drops of ferric chloride TS, and mix. To the deep red solution add about 50 mg of Edetate Disodium, and mix: the red color is discharged, leaving a yellowish solution.
C: It responds to the flame test for Sodium.
pH: between 4.0 and 6.0, in a solution (1 in 20).
Loss on drying: Dry it at 150 for 6 hours: it loses not less than 8.7% and not more than 11.4% of its weight.
Calcium: To a solution (1 in 20) add 2 drops of methyl red TS, and neutralize with 6 N ammonium hydroxide. Add 3 N hydrochloric acid drop-wise until the solution is just acid, and then add 1 mL of ammonium oxalate: no precipitate is formed.
Heavy metals: 0.005%.
Limit of nitrilotriacetic acid: not more than 0.1% of nitrilotriacetic acid is found.
Disodium Edetate BP Ph Eur
C10H14N2Na2O8,2H2O -- 372.2 -- CAS 139-33-3
Disodium dihydrogen (ethylenedinitrilo)tetraacetate dihydrate.
Content: 98.5 per cent to 101.0 per cent.
Appearance: White or almost white, crystalline powder.
Solubility: Soluble in water, practically insoluble in ethanol (96 per cent).
First identification A, B, D.
Second identification B, C, D.
A. Infrared absorption spectrophotometry.
B. Dissolve 2 g in 25 ml of water, add 6 ml of lead nitrate solution, shake and add 3 ml of potassium iodide solution. No yellow precipitate is formed. Make alkaline to red litmus paper by the addition of dilute ammonia. Add 3 ml of ammonium oxalate solution R. No precipitate is formed.
C. Dissolve 0.5 g in 10 ml of water and add 0.5 ml of calcium chloride solution. Make alkaline to red litmus paper by the addition of dilute ammonia and add 3 ml of ammonium oxalate solution. No precipitate is formed.
D. It gives the reactions of sodium.
Solution S: Dissolve 5.0 g in carbon dioxide-free water and dilute to 100 ml with the same solvent.
Appearance of solution: Solution S is clear and colourless.
pH: 4.0 to 5.5 for solution S.
Impurity A: Liquid chromatography. Carry out the test protected from light.
To pass the test
Limit: impurity A: not more than the area of the corresponding peak in the chromatogram obtained with the reference solution (0.1 per cent).
Iron: Maximum 80 ppm.
Heavy metals: Maximum 20 ppm
Specified impurities A
A. nitrilotriacetic acid.
Disodium EDTA FCC Food Grade
Disodium Ethylenediaminetetraacetate; Disodium (Ethylenedinitrilo)tetraacetate; Disodium Edetate
C10H14N2Na2O8·2H2O Formula wt 372.24
INS: 386 CAS: [CAS 6381-92-6]
EDTA Disodium occurs as a white, crystalline powder. It is soluble in water.
A. A 1:20 aqueous solution responds to the flame test for Sodium.
B. Add 2 drops of ammonium thiocyanate TS and 2 drops of ferric chloride TS to 5 mL of water in a test tube. Add about 50 mg of sample to the deep red solution so obtained, and mix. The deep red color disappears.
C. The infrared absorption spectrum of a potassium bromide dispersion of sample exhibits relative maxima at the same wavelengths as those of a similar preparation of USP Edetate Disodium Reference Standard.
Assay: Not less than 99.0% and not more than 101.0% of C10H14N2Na2O8·2H2O.
Lead: Not more than 10 mg/kg.
Nitrilotriacetic Acid: Not more than 0.1%.
pH of a 1:100 Solution: Between 4.3 and 4.7.
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Last updated 31-mar-21
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Disodium EDTA, Disodium Edetate IP BP Ph Eur EP USP FCC Food Grades Manufacturers