Calcium Gluceptate Glucoheptonate USP EP BP Ph Eur Manufacturers

Search for the supplies that you need here:

ISO-9001-14001-54001 JK Kosher Halal GMP GLP HACCP FSSAI Allergen free Star Export India
FSCC
FSCC 22000
Food Safety Systems Certification
cGMP, GLP - FDA Approved, ISO 9001, ISO 14001, ISO 17025, ISO 45001, HACCP, FSSC 22000, FSSAI, "REACH" Registered, Kosher & Halal Certified. We observe WHO Good Manufacturing Practice GMP and Good Laboratory Practice GLP
Excellence in Excipients and API Manufacturing .

DMF Support and Documentations Available

WHO-GMP Certified
Good Manufacturing Practice Certified by World Health Organization

WC, Written Confirmation
for Active Substance to be imported into European Union (EU).

Calcium Gluceptate USP or Calcium Glucoheptonate EP BP Ph Eur IP Grade Manufacturers

Anmol Chemicals is a manufacturer supplier exporter of Calcium Gluceptate or Calcium Glucoheptonate and it offers materials as per IP BP EP Ph Eur USP NF JP FCC Food Grade as per the the latest monograph at best prices. Anmol Chemicals Group, established in 1976, is the pioneer manufacturer of Specialty Chemicals, Pharmaceutical Excipients, Some API, Food Chemicals in India. Anmol Chemicals Group has manufacturing facilities spread across Western India, representatives in Houston, Chicago USA and Dubai, UAE. We also have toll manufacturing units for processing chemicals in a few countries around the world. We make IP, BP, EP, USP, NF, Ph. Eur., JP, FCC or Food Grade, Analytical Reagent Grade, LR or Laboratory Reagent Grades and Pure Grades of various chemicals. All our items are analyzed to meet the required standards. We can supply the product in grams for your laboratory trial and in tons for your plant scale jobs.

We manufacture Bulk Drugs / API, Excipients, Pharmaceuticals (IP BP USP NF Ph Eur EP JP), Specialty Chemicals (Pure/Reagent), Mineral Fortifiers (FCC). Our manufacturing facility is FDA approved and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) is available. Solid materials can be customized for particle size, shape, and bulk density. We observe WHO Good Manufacturing Practices and Good Laboratory Practices. We are a government-recognized STAR Export House and "Authorised Economic Operator (AEO)" per Indian Customs.

Synonyms: Calcium Gluceptate or Calcium Glucoheptonate
CAS Number: 29039-00-7 (also quoted is 17140-60-2), Molecular Weight: 490.42, Chemical Formula: C14H26CaO16, EINECS EC Number: ----, FEMA: ----,

Calcium Gluceptate USP Grade Specifications
C14H26CaO16 (anhydrous) -- 490.42
Glucoheptonic acid, calcium salt (2:1).
Calcium glucoheptonate (1:2) -- [CAS 29039-00-7].

Calcium Gluceptate is anhydrous or contains varying amounts of water of hydration. It consists of the calcium salt of the alpha epimer of glucoheptonic acid or of a mixture of the alpha and beta epimers of glucoheptonic acid. It contains not less than 95.0 percent and not more than 102.0 percent of C 14H26CaO16, calculated on the dried basis.

Labeling: Label it to indicate whether it is hydrous or anhydrous; if hydrous, label it to indicate also the degree of hydration.

Identification:
A: Infrared Absorption 197K.
B: A solution (1 in 50) responds to the tests for Calcium 191 .
pH: between 6.0 and 8.0, in a solution (1 in 10).
Loss on drying: [NOTE—The quantity taken for the determination may be adjusted, if necessary, for instrument sensitivity. Weight loss occurring at temperatures above about 160 degree indicative of decomposition, is not to be interpreted as Loss on drying.] Determine the percentage of volatile substances by thermogravimetric analysis on an appropriately calibrated instrument, using 10 to 25 mg of Calcium Gluceptate accurately weighed. Heat the specimen under test at a rate of 5 degrees per minute in an atmosphere of nitrogen, at a flow rate of 40 mL per minute. Record the thermogram to 150 degree: the anhydrous form loses not more than 1.0%, the 2H2O form not more than 6.9%, and the 3½H2O form not more than 11.4%, of its weight.
Chloride: A 1.0-g portion shows no more chloride than corresponds to 1.0 mL of 0.020 N hydrochloric acid (0.07%).
Sulfate: A 2.0-g portion shows no more sulfate than corresponds to 1.0 mL of 0.020 N sulfuric acid (0.05%).
Heavy metals: Dissolve 1 g in 25 mL of water: the limit is 0.002%.
Reducing sugars: Dissolve 0.50 g in 10 mL of hot water, add 2 mL of 3 N hydrochloric acid, boil for about 2 minutes, and cool. Add 5 mL of sodium carbonate, allow to stand for 5 minutes, dilute with water to 20 mL, and filter. Add 5 mL of the clear filtrate to about 2 mL of alkaline cupric tartrate and boil for 1 minute: no red precipitate is formed immediately.
Assay: Dissolve about 800 mg of Calcium Gluceptate, accurately weighed, in 150 mL of water containing 2 mL of 3 N hydrochloric acid. While stirring, preferably with a magnetic stirrer, add about 25 mL of 0.05 M EDTA disodium from a 50-mL buret. Add 15 mL of 1 N sodium hydroxide and 300 mg of hydroxy naphthol blue, and continue the titration to a blue endpoint. Each mL of 0.05 M EDTA disodium is equivalent to 24.52 mg of C14H26CaO16.

Calcium Glucoheptonate BP Ph Eur Grade Specifications
Ph Eur
C14H26CaO16 -- 490.4 -- CAS 29039-00-7
Action and use: Used in treatment of calcium deficiency.

DEFINITION
Mixture in variable proportions, of calcium di(D-glycero-D-gulo-heptonate) and calcium di (D-glycero-D-ido-heptonate).
Content: 98.0 per cent to 102.0 per cent of calcium 2,3,4,5,6,7-hexahydroxyheptanoate (dried substance).

CHARACTERS
Appearance: White or very slightly yellow, amorphous powder, hygroscopic.
Solubility: Very soluble in water, practically insoluble in acetone and in ethanol (96 per cent).

IDENTIFICATION
A. Thin-layer chromatography.
B. 0.2 ml of (see Tests) gives reaction (b) of calcium.

TESTS
Solution S: Dissolve 10.0 g in carbon dioxide-free water prepared from distilled water and dilute to 100 ml with the same solvent.
Appearance of solution: Solution S is clear and not more intensely coloured than reference solution.
pH: 6.0 to 8.0 for solution S.
Reducing sugars: Maximum 1 per cent, expressed as glucose.
Cyanide: To pass the test.
Chlorides: Maximum 100 ppm.
Sulphates: Maximum 100 ppm, determined on solution S.
Iron: Maximum 40 ppm.
Heavy metals: Maximum 10 ppm.
Loss on drying: Maximum 5.0 per cent, determined on 1.000 g by drying in an oven at 105C for 3 h.
Bacterial endotoxins: Less than 167 IU/g, if intended for use in the manufacture of parenteral dosage forms without a further appropriate procedure for the removal of bacterial endotoxins.
ASSAY: Dissolve 0.800 g in a mixture of 150 ml of water and 2 ml of 3 M hydrochloric acid . While stirring, add 12.5 ml of 0.1 M sodium EDTA , 15 ml of 1 M sodium hydroxide and 0.3 g of hydroxynaphthol blue, sodium salt. Titrate with 0.1 M sodium EDTA until the colour changes from violet to pure blue.
1 ml of 0.1 M sodium EDTA is equivalent to 49.04 mg of C14H26CaO16.

Keywords: Calcium Gluceptate, Calcium Glucoheptonate, Glucoheptonic Acid Calcium Salt IP BP Ph Eur EP USP Analytical Reagent FCC Food Grade CAS Number 29039-00-7 17140-60-2 Manufacturer Supplier Exporter Monograph Uses Chemical Molecular Formula Weight.

ANMOL CHEMICALS
Now maturing as Anmol Chemicals Private Limited
Representatives in Houston, Chicago and New York, USA
TEL: (OFF) +91 22 23726950, +91 22 23774610, +91 22 23723564
Taloja Navi Mumbai, INDIA

Exporters to USA, Canada, UAE, Kwait, Qatar, Gautemala, Tunisia, Europe, South Africa, Bangladesh, Sri Lanka, Tanzania, Kenya, Egypt, Iraq, Turkey, Israel, Vietnak, Nigeria, Uganda, Brazil, Chile, Argentina, Dubai, UAE, Saudi Arabia, Cameroon, Mexico, Brazil, Chile, Argentina, Korea, Thailand, Malaysia, Indonesia, Jakarta, Australia, China, Germany, France, etc.

Representatives in New York, Houston - Texas, Chicago - Illinois, Los Angeles.