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Bismuth Subsalicylate USP BP Manufacturers
Anmol Chemicals Group, established in 1976, is the pioneer manufacturer of Specialty chemicals, Pharmaceutical Excipients, Fragrance & Flavor chemicals in India. Anmol Chemicals Group has manufacturing facilities spread across Western India, representatives in Houston Chicago USA, Dubai and UAE. We also have toll manufacturing units for processing chemicals in a few countries around the world. We make IP, BP, USP, Ph. Eur., FCC or Food Grade, Analytical Reagent Grade, LR or Laboratory Reagent Grade, Pure and Technical Grades of various chemicals. All our items are analyzed to meet the required standards. We can supply the material in grams for your laboratory trial and in tons for your plant scale jobs.
Our manufacturing facility is FDA approved and cGMP, GLP (FDA) Approved, ISO 9001, ISO 14001, ISO 17025, ISO 45001, ISO 22000, HACCP, FSSAI, FSSC 22000, Halal and Kosher certified. We are registered with "REACH" for export to European countries. Solid materials can be customized for particle size, shape and bulk density. We observe WHO Good Manufacturing Practice and Good Laboratory Practice. We are a STAR Export House and “Authorised Economic Operator” as per Indian customs.
Bismuth Subsalicylate SDS of BP USP Manufacturers
Synonyms: Bismuth oxysalicylate, Bismuth(III) subsalicylate, Bismuth(III) salicylate basic
CAS Number: 14882-18-9, Molecular Weight: 362.09, Chemical Formula: HOC6H4COOBiO, EINECS EC Number: 238-953-1, FEMA: ----,
Bismuth Subsalicylate BP Grade
362.1 -- 14882-18-9
Complex of bismuth and salicylic acid.
Content: 56.0 per cent to 59.4 per cent of Bi (Ar 209.0) (dried substance).
Appearance: White or almost white powder.
Solubility: Practically insoluble in water and in alcohol. It dissolves in mineral acids with decomposition.
A. To 0.5 g add 10 ml of hydrochloric acid. Heat on a boiling water-bath for 5 min. Cool and filter. Retain the filtrate for identification test B. Wash the residue with dilute hydrochloric acid and then with water. Dissolve the residue in 0.5-1 ml of dilute sodium hydroxide solution. Add 15 ml of water. Neutralise with dilute hydrochloric acid. The solution gives reaction (a) of salicylates.
B. The filtrate obtained in identification test A gives reaction (b) of bismuth.
Solution S: In a porcelain or quartz dish, ignite 1.0 g, increasing the temperature very gradually. Heat in a muffle furnace at 600 ± 25C for 2 h. Cool and dissolve the residue with warming in 4 ml of a mixture of equal volumes of lead-free nitric acid and water and dilute to 20 ml with water.
Acidity: Shake 2.0 g with 30 ml of ether for 1 min and filter. To the filtrate add 30 ml of alcohol and 0.1 ml of thymol blue solution. Not more than 0.35 ml of 0.1 M sodium hydroxide is required to change the colour of the indicator to blue.
Chlorides: Maximum 200 ppm.
Nitrates: Maximum 0.4 per cent.
Copper: Maximum 50.0 ppm.
Lead: Maximum 20.0 ppm.
Silver: Maximum 25.0 ppm.
Soluble bismuth: Maximum 40.0 ppm.
Loss on drying: Maximum 1.0 per cent, determined on 1.000 g by drying in an oven at 105C.
Dissolve with heating 0.300 g in 10 ml of a mixture of 2 volumes of perchloric acid and 5 volumes of water. To the hot solution, add 200 ml of water and 50 mg of xylenol orange triturate. Titrate with 0.1 M sodium edta until a yellow colour is obtained.
1 ml of 0.1 M sodium edta is equivalent to 20.90 mg of Bi.
Bismuth Subsalicylate USP Grade
C7H5BiO4 -- 362.09
2-Hydroxybenzoic acid bismuth (3+) salt, basic [14882-18-9].
Bismuth Subsalicylate is a basic salt that when dried at 105 for 3 hours contains not less than 56.0 percent and not more than 59.4 percent of bismuth (Bi) and not less than 36.5 percent and not more than 39.3 percent of total salicylates.
A: Infrared Absorption.
B: It responds to the tests for Bismuth.
pH: between 2.7 and 5.0, in a solution prepared as follows. Mix 10 g of Bismuth Subsalicylate and 90 mL of water, shake by mechanical means for 10 minutes, and filter.
Loss on drying: Dry it at 105C for 3 hours: it loses not more than 1.0% of its weight.
Limit of nitrate: 0.4%.
Arsenic: The limit is 10 µg per g.
Limit of free salicylic acid: To pass the test. (Not more than 0.2%).
Limit of copper, lead, and silver: To pass the test. (40 µg per g).
Taloja Mumbai and Ankleshwar, INDIA
Representatives in Houston, Chicago and New York, USA
TEL: (OFF) +91 22 23726950, +91 22 23774610, +91 22 23723564
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Last updated 31-mar-21
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